# AstraZeneca: Phase 3 study closed enrollment, 1350 enrolled (NSCLC)

**Score:** 75/100

| Field | Value |
|---|---|
| Sponsor | AstraZeneca |
| Sponsor type | Industry (pharma, biotech, medtech) |
| Study | Phase III, Open-label, First-line Study of Dato-DXd in Combination With Durvalumab and Carboplatin for Advanced NSCLC Without Actionable Genomic Alterations |
| NCT ID | NCT05687266 |
| Phase | Phase 3 |
| Status | active not recruiting |
| Conditions | NSCLC |
| Intervention types | drug |
| Target enrollment | 1350 |
| Site countries | United States, Austria, Brazil, Bulgaria, Canada, China, France, Germany, Greece, Hungary, India, Italy |
| Posted | 2023-01-18 |
| Planned start | 2022-12-29 |
| Event | Enrollment closed (active, not recruiting) |
| Event date | 2026-10-09 |
| Last update posted | 2026-10-09 |

## Why this score
- Industry sponsor (buys outsourced services).
- Enrollment closed: data management, monitoring and closeout ahead.
- Phase 3: multi-site, larger budget.
- 1350 participants planned.

Source: ClinicalTrials.gov (U.S. National Library of Medicine) API v2 (https://clinicaltrials.gov/study/NCT05687266). Last refreshed: 2026-11-04T06:04:38.232Z.
From public ClinicalTrials.gov registrations. Sponsor and study level only: we never list investigators, contacts or participants. A registration describes a planned study and can change. Status changes are read from each study's current status, actual dates and latest posted update, not a full change history, so an update can be a correction rather than a new change. Verify on ClinicalTrials.gov.