# National Cancer Institute (NCI): Observational study closed enrollment, 500 enrolled (Macrophage Activation Syndrome, Primary Hemophagocytic Lymphohistiocytosis)

**Score:** 40/100

| Field | Value |
|---|---|
| Sponsor | National Cancer Institute (NCI) |
| Sponsor type | NIH |
| Study | Retrospective Study of Immunotherapy Related Toxicities and Factors Impacting Outcomes in Children and Adults With Cancer |
| NCT ID | NCT03827343 |
| Phase | Observational |
| Status | active not recruiting |
| Conditions | Macrophage Activation Syndrome; Primary Hemophagocytic Lymphohistiocytosis |
| Target enrollment | 500 |
| Site countries | United States |
| Posted | 2019-02-01 |
| Planned start | 2019-01-23 |
| Event | Enrollment closed (active, not recruiting) |
| Event date | 2026-10-08 |
| Last update posted | 2026-10-08 |

## Why this score
- Enrollment closed: data management, monitoring and closeout ahead.
- 500 participants planned.

Source: ClinicalTrials.gov (U.S. National Library of Medicine) API v2 (https://clinicaltrials.gov/study/NCT03827343). Last refreshed: 2026-11-05T08:46:16.625Z.
From public ClinicalTrials.gov registrations. Sponsor and study level only: we never list investigators, contacts or participants. A registration describes a planned study and can change. Status changes are read from each study's current status, actual dates and latest posted update, not a full change history, so an update can be a correction rather than a new change. Verify on ClinicalTrials.gov.