# Request for Information; Clinical Laboratory Improvement Amendments of 1988 (CLIA) Regulations

**Action Urgency Score:** 20/100

| Field | Value |
|---|---|
| Agency | Health and Human Services Department; Centers for Medicare & Medicaid Services |
| Type | Proposed rule |
| Action | Request for information. |
| Published | 2026-07-16 |
| Comments close | 2026-09-14 |
| Significant | No |
| CFR parts | 42 CFR 493 |
| Summary | Clinical laboratory testing technology has advanced significantly since the Clinical Laboratory Improvement Amendments of 1988 (CLIA) regulations were implemented in 1992. This request for information (RFI) seeks input from the public regarding various topics related to the CLIA regulations, including: breath testing; laboratory processes and procedures; emergency preparedness, biosafety and biosecurity, and cybersecurity; and specialty testing areas. Responses to this RFI may be used to help inform CMS and the CDC as to what types of action, if any, should be taken to update the existing CLIA |
| Document number | 2026-14358 |

## Why this score


Source: Federal Register API (Office of the Federal Register) (https://www.federalregister.gov/documents/2026/07/16/2026-14358/request-for-information-clinical-laboratory-improvement-amendments-of-1988-clia-regulations). Last refreshed: 2026-11-04T21:40:49.974Z.
Data from the Federal Register API; the published Federal Register document is authoritative. Informational only, not legal advice.