# The Genesis Mission:  Transforming Science and Energy with AI (DE-FOA-0003612)

**Plain-English Eligibility Score:** 55/100

| Field | Value |
|---|---|
| Opportunity number | DE-FOA-0003612 |
| Title | The Genesis Mission:  Transforming Science and Energy with AI |
| Agency | Office of Science |
| Status | posted |
| Posted / open date | 2026-03-17 |
| Close date | 2026-12-17 |
| Award ceiling | $16,000,000 |
| Award floor | $500,000 |
| Estimated total funding | $293,760,000 |
| Funding category | Science and Technology and other Research and Development |
| Eligible applicants | Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled "Additional Information on Eligibility" |
| CFDA / Assistance listing | 81.049 |
| Summary | The DOE Office of Science (SC), Office of Critical Minerals and Energy Innovation (CMEI), Office of Environmental Management (EM), Office of Nuclear Energy (NE), Office of Electricity (OE), and Hydrocarbons and Geothermal Office (HGEO) hereby announce interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and research and development (R&D) workflows using novel artificial intelligence (AI) models and frameworks. By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear ch |
| Agency contact | GenesisMissionNOFO@science.doe.gov |

## Why this score
- Eligibility is unrestricted.
- 42 days until the deadline: enough time to prepare a strong application.

Source: Grants.gov (U.S. Department of Health and Human Services) (https://www.grants.gov/search-results-detail/361526). Last refreshed: 2026-11-04T18:11:59.874Z.
Data from Grants.gov. Always read the full notice of funding opportunity before applying. Informational only; not legal or grant-writing advice.