# UNIV OF MASSACHUSETTS MED SCH WORCESTER: Advancing XIST-based Epigenetics for Dosage Disorders:  Silencing Trisomy 21 or Specific Chromosome Regions in Down Syndrome Mice and Human Organoids

**Lab Budget Score:** 55/100

| Field | Value |
|---|---|
| Organization | UNIV OF MASSACHUSETTS MED SCH WORCESTER |
| Location | WORCESTER, MA |
| Project | Advancing XIST-based Epigenetics for Dosage Disorders:  Silencing Trisomy 21 or Specific Chromosome Regions in Down Syndrome Mice and Human Organoids |
| Project number | 2R56HD094788-06A1 |
| Mechanism | R56 |
| Institute | Eunice Kennedy Shriver National Institute of Child Health and Human Development |
| Award | $600,000 |
| Awarded | 2026-08-28 |
| Project period | 2018-09-19 to 2027-08-31 |
| UEI | MQE2JHHJW9Q8 |

## Why this score
- Award of $400K or more.
- Research or center grant: supplies, instruments and services budget.

Source: NIH RePORTER (newly awarded projects) (https://reporter.nih.gov/project-details/11600903). Last refreshed: 2026-11-04T21:37:56.465Z.
Award data comes from NIH RePORTER and may be revised by NIH. Organization-level only; investigator names and contacts are not included. Informational only.