HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) (RFA-NS-27-007)
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional): Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) (RFA-NS-27-007). Dated 141 days ago, it serves as a historical benchmark. Score 80/100. As of 2026-11-03, from Grants.gov (U.S. Department of Health and Human Services).
Data as of · Compiled by Zalwin from Grants.gov (U.S. Department of Health and Human Services)
Free preview: all 15 published fields of this record are shown below. Locked: 111 related GrantPulse records and the 5-column CSV export.
| Field | Value |
|---|---|
| Opportunity number | RFA-NS-27-007 |
| Title | HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) |
| Agency | National Institutes of Health |
| Status | posted |
| Posted / open date | 2026-06-16 |
| Close date | 2029-02-20 |
| Award ceiling | n/a |
| Award floor | n/a |
| Estimated total funding | $11,000,000 |
| Funding category | Health |
| Eligible applicants | State governments; County governments; Native American tribal organizations (other than Federally recognized tribal governments); Private institutions of higher education; City or township governments; Others (see text field entitled "Additional Information on Eligibility" for clarification); Special district governments; Public housing authorities/Indian housing authorities; Small businesses; Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education; Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education; Native American tribal governments (Federally recognized); For profit organizations other than small businesses; Public and State controlled institutions of higher education; Independent school districts |
| Eligibility notes | Refer to Section III. Eligibility Information in the NOFO for additional information on eligibility.Foreign Organizations/International CollaborationsNon-domestic (non-U.S.) Entities (Foreign Organizations) are not eligible to apply.Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.Foreign components, as defined in the NIH Grants Policy Statement, are not allowed. |
| CFDA / Assistance listing | 93.395, 93.866, 93.839, 93.867, 93.838, 93.846, 93.840, 93.213, 93.273, 93.853, 93.837, 93.233, 93.279, 93.865 |
| Summary | The purpose of this Notice of Funding Opportunity (NOFO) is to support the preclinical optimization and development of safe, effective, and non-addictive small molecule and biologic therapeutics for the treatment of pain. The goal of the program is to accelerate the advancement of promising early-stage therapeutic candidates and facilitate their readiness for Phase II clinical trials. Applicants must have a promising small molecule or biologic lead candidate for optimization, a strong biological rationale for the proposed approach, and established assays to guide the optimization process. The scope of the program includes lead optimization, early-stage development activities, IND-enabling st |
| Agency contact | [email protected] |
| Peer records CSV (112 records) | 🔒 Click to unlock → |
| CRM-ready export with official source URLs | 🔒 Click to unlock → |
Watch HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)
Free email alert. Alert me when this company gets a new filing, lien, permit, contract or expiry in this feed. One confirmation email; unsubscribe any time.
Free for 1 company. More companies from $9/mo (25), $49/mo (500 + CSV), $199/mo (500 + CSV + API). Cancel any time from the link in every email.
Free first: a 10-record sample of records
See the real columns before you buy. One confirmation email, nothing else unless you opt in.
Unlock HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) + all 112 records (CSV)
Instant CSV download · Card, Apple Pay, Google Pay or Link via Stripe · No account required
CSV columns: Opportunity · Agency · Status · Award ceiling · Closes · official source URL
- Source agency: Grants.gov (U.S. Department of Health and Human Services)
- Record date: 2026-06-16
- Data refreshed: 2026-11-03
- Refunds on request within 14 days
Top GrantPulse records (HHS first): Children’s Hospitals Graduate Medical Education (CHGME · Centers of Excellence in Healthcare Quality and Safety (CDC- · Title X Family Planning Services Grants (PA-FPH-27-001) · Development of Collaborative Research Facilities or Research · Emerging Infections Network - Research for Preventing, Detec · Browse all by state and category →
LIVE PUBLIC DATA Source: Grants.gov (U.S. Department of Health and Human Services) · Last refreshed: Tue, 03 Nov 2026 18:08:06 GMT
Is this your business? Add a "Listed on Zalwin" badge to your site
Paste this snippet into your website. It links to this public record; nothing is tracked on your site.
Peer benchmark and outreach value: HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) and 112 HHS peers
- HHS GrantPulse records like this one: 112
- Timing: Low: older than 30 days
- Estimated pipeline if you contact every HHS peer: $22,400 (peers × rate × deal size; an estimate from your assumptions, not a forecast)
80 / 100 Plain-English Eligibility Score
- Small businesses are listed as eligible applicants.
- Nonprofits are listed as eligible applicants.
- 839 days until the deadline: enough time to prepare a strong application.
What is the GrantPulse record for HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional)?
HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) (RFA-NS-27-007) from National Institutes of Health: posted, award ceiling n/a.
How does HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) compare to other GrantPulse records?
It is 141 days old; check the official source for later updates before acting. Its Plain-English Eligibility Score of 80/100 puts it among the stronger signals in this feed.
Get the readiness pack for this opportunity ($4.99)
Eligibility summary, registrations checklist, deadline timeline and a proposal outline, generated from this notice.
HEAL Initiative vs. top 3 peers
| Organization | Location | Combined award ceilings | Percentile | Record date |
|---|---|---|---|---|
| HEAL Initiative | HHS | 2026-06-16 | ||
| Rural Communities Opioid Response Program - Overdose Response | HHS | $300,000 | 19th | 2026-08-21 |
| Rural Communities Opioid Response Program - Child and Adolescent Behavioral Health | HHS | $1,000,000 | 59th | 2026-08-21 |
| Rural Communities Opioid Response Program - Community Systems Development | HHS | $500,000 | 35th | 2026-08-14 |
Related records
- Rural Communities Opioid Response Program - Overdose Response
- Rural Communities Opioid Response Program - Child and Adolescent Behavioral Health
- Rural Communities Opioid Response Program - Community Systems Development
- Healthy Tomorrows Partnership for Children Program (HTPCP)
- Rural Residency Planning and Development Program
- Rural Health Value Program
- The National Network of STI Prevention Training Centers (NNPTC)
- Comprehensive Suicide Prevention Program for States
- NIOSH Small Research Grant Program (R03)
- NIOSH National Center of Excellence for the Prevention of Childhood Agricultural Injury (U54)
- Research Grants to Rigorously Evaluate Innovative and Promising Approaches to Prevent Firearm-Related Violence and Injuries
- Cooperative Research Agreements Related to the World Trade Center Health Program (U01)
Open and upcoming HHS federal grants Open and upcoming federal grants: Health
How to monitor HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) and peer health records
Get new GrantPulse records like HEAL Initiative: Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] to Treat Pain (UG3/UH3 Clinical Trial Optional) by email (free, weekly)
We email one confirmation link now; the weekly digest starts only after you confirm. One-click unsubscribe in every email.
Double opt-in: nothing is sent until you click the confirmation link. One-click unsubscribe.
Get new grants that fit you every week
GrantPulse emails new and forecasted grants matching your organization type and focus areas.
✓ Read-only, live public data · Key and unlock right after payment · Card, Apple Pay, Google Pay or Link via Stripe · Refunds on request within 14 days
Data from Grants.gov. Always read the full notice of funding opportunity before applying. Informational only; not legal or grant-writing advice.
Often used together
- FormDPulse
- NsfAwardPulse
- Public Works Prevailing Wage Intent + Environmental Remediation & Tank Retrofit Multi-Signal Trigger
- ContentVelocityRadar
- B2BDomainSignalVerify
- PodcastSponsorRadar
Or get the Advisor Prospecting Bundle for $14.99 one-time: Full CSV unlock of newly funded companies plus a grant readiness pack.